Measuring mathod
- Gestational Age: Ideally between 11 weeks 0 days to 13 weeks 6 days.
- Crown-Rump Length (CRL): Between 45 mm and 84 mm.
- Fetal Position: Midsagittal plane of the fetus with neutral head position—not flexed or hyperextended.
- Magnification: The fetal head and thorax should fill at least 75% of the image.
- Caliper Placement: Measure the maximum lucency at the back of the fetal neck—inner-to-inner margins of the nuchal space.
- Image Settings: High contrast and clear resolution. Amniotic membrane should be distinguishable from the NT space.
- Number of Measurements: Take at least 3 measurements and record the highest consistent one.
- Exclude: Do not include the amnion or fetal skin in the measurement.
What If NT is High?
- Down syndrome (Trisomy 21)
- Edwards syndrome (Trisomy 18)
- Patau syndrome (Trisomy 13)
- Turner syndrome (Monosomy X)
- Congenital heart defects (most common)
- Diaphragmatic hernia
- Skeletal dysplasias
- Noonan syndrome
- Other single-gene disorders
- Miscarriage
- Fetal death
- Intrauterine growth restriction (IUGR)
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- Down syndrome (Trisomy 21)Edwards syndrome (Trisomy 18)
- Chorionic Villus Sampling (CVS) at 11–13 weeks
- Amniocentesis after 15 weeks

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