Forehead-to-Nasal Tip Ratio

Forehead-to-Nasal Tip Ratio

Fronto-Maxillary Facial (FMF) Angle

  • Definition: Angle between the line along the upper surface of the maxilla and the line along the frontal bone.
  • Normal Range: ~76–83° at 11–13+6 weeks
  • Clinical Relevance: Helps assess facial disproportions or micrognathia
  • Increased FMF Angle: Associated with Down syndrome (Trisomy 21)
  • How to Measure:
    • Mid-sagittal view of the face
    • One line: along the upper aspect of the maxilla
    • Second line: tangential to the frontal bone
    • Measure the angle between these two lines

Forehead-to-Nasal Tip Ratio

  • This is a relatively rarely used soft marker assessed during first-trimester NT (Nuchal Translucency) screening.
  • It is a craniofacial ratio calculated on a mid-sagittal plane ultrasound image using two linear measurements:
    • Forehead Length: From the leading edge of the frontal bone to the nasion (root of the nose).
    • Nasal Tip Length: From the nasion to the nasal tip.
    • Formula: Forehead-to-Nasal Tip Ratio = Forehead Length / Nasal Tip Length

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